I am a fourth-year PhD student in Medical Engineering and Medical Physics at the Harvard-MIT Program in Health Sciences and Technology, advised by Elazer Edelman and Farhad Nezami. I have a M.Sc in Bioengineering from EPFL and a dual bachelor’s degree in Mechanical Engineering and Physics from the American University in Cairo.

I am interested in integrating generative models of 3D anatomic shape with computational simulators of medical devices to understand how anatomic form impacts interventional outcomes. More specifically I focus on equipping diffusion models with geometric and topological control mechanisms to edit patient-specific anatomy and create digital siblings. Simulating both patient and sibling enables clinical researchers and device designers to find counterfactual shape features that causally influence simulated device outcomes, leading to safer and more effective medical devices.

Selected Publications (full list)

A Diffusion Model for Simulation Ready Coronary Anatomy with Morpho-skeletal Control
Paper | Download Here
Probing the Limits and Capabilities of Diffusion Models for the Anatomic Editing of Digital Twins
Paper | Download Here
Morphology-based non-rigid registration of coronary computed tomography and intravascular images through virtual catheter path optimization
Paper | Download Here
Fully automated construction of three-dimensional finite element simulations from Optical Coherence Tomography
Paper | Download Here
A platform for high-fidelity patient-specific structural modelling of atherosclerotic arteries: from intravascular imaging to three-dimensional stress distributions
Paper | Download Here
Biomechanics of Diastolic Dysfunction: A One-Dimensional Computational Modeling Approach
Paper | Download Here